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Overview: In this case study, students investigate the origin and action of mutations that are thought to have arisen in human populations in response to selection pressure from malaria. Author/Source: DNA to Darwin Grade level: 13-16 Time: 1-2 hours Teaching tips: Use this resource to relate evolutionary concepts to the topics of transcription and translation (or get more suggestions for incorporating evolution throughout your biology syllabus). Concepts: Correspondence to the Next Generation Science Standards is indicated in parentheses after each relevant concept. See our conceptual framework for details. - There is a fit between organisms and their environments, though not always a perfect fit.
- Evolution results from natural selection acting upon genetic variation within a population.
- Depending on environmental conditions, inherited characteristics may be advantageous, neutral, or detrimental.
- Natural selection sometimes favors heterozygotes over homozygotes at a locus.
- A hallmark of science is exposing ideas to testing.
- Scientists use multiple research methods (experiments, observational research, comparative research, and modeling) to collect data.
- Scientists can test ideas about events and processes long past, very distant, and not directly observable.
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