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Lesson summary for:
DNA to Darwin: Malaria and the human genome

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Overview:
In this case study, students investigate the origin and action of mutations that are thought to have arisen in human populations in response to selection pressure from malaria.

Author/Source:
DNA to Darwin

Grade level:
13-16

Time:
1-2 hours

Teaching tips:
Use this resource to relate evolutionary concepts to the topics of transcription and translation (or get more suggestions for incorporating evolution throughout your biology syllabus).

Concepts:
Correspondence to the Next Generation Science Standards is indicated in parentheses after each relevant concept. See our conceptual framework for details.

  • There is a fit between organisms and their environments, though not always a perfect fit.

  • Evolution results from natural selection acting upon genetic variation within a population.

  • Depending on environmental conditions, inherited characteristics may be advantageous, neutral, or detrimental.

  • Natural selection sometimes favors heterozygotes over homozygotes at a locus.

  • A hallmark of science is exposing ideas to testing.

  • Scientists use multiple research methods (experiments, observational research, comparative research, and modeling) to collect data.

  • Scientists can test ideas about events and processes long past, very distant, and not directly observable.

Teacher background:

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