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Overview: Students compare the sequence of amino acids in a gene shared between humans and six other organisms and infer evolutionary relationships among the species. Author/Source: NOVA Grade level: 9-12 Time: 1 hour Teaching tips: The video and worksheet are each worthwhile but could easily be used separately. Concepts: Correspondence to the Next Generation Science Standards is indicated in parentheses after each relevant concept. See our conceptual framework for details. Biological evolution accounts for diversity over long periods of time. (LS4.A, LS4.D) Present-day species evolved from earlier species; the relatedness of organisms is the result of common ancestry. (LS4.A) Similarities among existing organisms provide evidence for evolution. (LS4.A) All life forms use the same basic DNA building blocks. (LS4.A) Scientists use the similarity of DNA nucleotide sequences to infer the relatedness of taxa. (LS4.A) Evolutionary trees (i.e., phylogenies or cladograms) portray hypotheses about evolutionary relationships. Teacher background: Classification/Phylogenetics Genetic Variation

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