• [Evidence of evolution: Grades 9-12] There is a fit between organisms and their environments, though not always a perfect fit. (LS4.C)
• [Evidence of evolution: Grades 13-16] There is a fit between organisms and their environments, though not always a perfect fit.
• [Mechanisms of evolution: Grades 9-12] Evolution results from selection acting upon genetic variation within a population. (LS4.B)
• [Mechanisms of evolution: Grades 9-12] Inherited characteristics affect the likelihood of an organism's survival and reproduction. (LS4.B, LS4.C)
• [Mechanisms of evolution: Grades 9-12] Traits that confer an advantage may persist in the population and are called adaptations. (LS4.B, LS4.C)
• [Mechanisms of evolution: Grades 9-12] Over time, the proportion of individuals with advantageous characteristics may increase due to their likelihood of surviving and reproducing. (LS4.B, LS4.C)
• [Mechanisms of evolution: Grades 9-12] Depending on environmental conditions, inherited characteristics may be advantageous, neutral, or detrimental.
• [Mechanisms of evolution: Grades 13-16] Evolution results from natural selection acting upon genetic variation within a population.
• [Mechanisms of evolution: Grades 13-16] Natural selection and genetic drift act on the variation that exists in a population.
• [Mechanisms of evolution: Grades 13-16] Inherited characteristics affect the likelihood of an organism's survival and reproduction.
• [Mechanisms of evolution: Grades 13-16] Over time, the proportion of individuals with advantageous traits may increase (and the proportion with disadvantageous traits may decrease) due to their chances of surviving and reproducing.
• [Mechanisms of evolution: Grades 13-16] Traits that confer an advantage may persist in the population and are called adaptations.
• [Mechanisms of evolution: Grades 13-16] Depending on environmental conditions, inherited characteristics may be advantageous, neutral, or detrimental.
• [Nature of science: Grades 9-12] Scientific knowledge is open to question and revision as we come up with new ideas and discover new evidence. (P4, P6, NOS3)
• [Nature of science: Grades 9-12] A hallmark of science is exposing ideas to testing. (P3, P4, P6, P7)
• [Nature of science: Grades 9-12] Scientists test their ideas using multiple lines of evidence. (P6, NOS2)
• [Nature of science: Grades 9-12] Scientists use multiple research methods (experiments, observational research, comparative research, and modeling) to collect data. (P2, P3, P4, NOS1)
• [Nature of science: Grades 9-12] Scientists can test ideas about events and processes long past, very distant, and not directly observable.
• [Nature of science: Grades 9-12] The real process of science is complex, iterative, and can take many different paths.
• [Nature of science: Grades 9-12] Accepted scientific theories are not tenuous; they must survive rigorous testing and be supported by multiple lines of evidence to be accepted. (NOS2, NOS4)
• [Nature of science: Grades 9-12] Science is a human endeavor. (NOS7)
• [Nature of science: Grades 13-16] A hallmark of science is exposing ideas to testing.
• [Nature of science: Grades 13-16] Scientists test their ideas using multiple lines of evidence.
• [Nature of science: Grades 13-16] Scientists use multiple research methods (experiments, observational research, comparative research, and modeling) to collect data.
• [Nature of science: Grades 13-16] Scientists can test ideas about events and processes long past, very distant, and not directly observable.
• [Nature of science: Grades 13-16] The real process of science is complex, iterative, and can take many different paths.
• [Nature of science: Grades 13-16] Accepted scientific theories are not tenuous; they must survive rigorous testing and be supported by multiple lines of evidence to be accepted.
• [Nature of science: Grades 13-16] Science is a human endeavor.
• [Studying evolution: Grades 9-12] Scientists use experimental evidence to study evolutionary processes.
• [Studying evolution: Grades 13-16] Scientists use experimental evidence to study evolutionary processes.

• Disciplinary Core Idea LS4.B: Natural Selection
• Disciplinary Core Idea LS4.C: Adaptation
• NOS Matrix understanding category 1. Scientific investigations use a variety of methods.
• NOS Matrix understanding category 2. Scientific knowledge is based on empirical evidence.
• NOS Matrix understanding category 3. Scientific knowledge is open to revision in light of new evidence.
• NOS Matrix understanding category 4. Scientific models, laws, mechanisms, and theories explain natural phenomena.
• NOS Matrix understanding category 7. Science is a human endeavor.
• Science and Engineering Practice 2. Developing and using models
• Science and Engineering Practice 3. Planning and carrying out investigations
• Science and Engineering Practice 4. Analyzing and interpreting data
• Science and Engineering Practice 6. Constructing explanations and designing solutions
• Science and Engineering Practice 7. Engaging in argument from evidence

9-12 teaching tips:
This case study includes entertaining cartoons. You might cap study of this article by showing students a part of PBS's Evolution video that highlights this arms race: http://www.pbs.org/wgbh/evolution/library/01/3/l_013_07.html

13-16 teaching tips:
Use this resource to relate evolutionary concepts to the nature and process of science (or get more suggestions for incorporating evolution throughout your biology syllabus).

• Adaptation
• Evidence for Evolution
• Nature of Science